BMJ Open (Jun 2023)
Optimising the care for older persons with complex chronic conditions in home care and nursing homes: design and protocol of I-CARE4OLD, an observational study using real-world data
- ,
- John P Hirdes,
- Hao Luo,
- Davide L Vetrano,
- Graziano Onder,
- Jonathan Chen,
- Violetta Kijowska,
- Katarzyna Szczerbińska,
- Johanna Edgren,
- Amaia Calderón-Larrañaga,
- George Heckman,
- Ron MC Herings,
- Johanna de Almeida Mello,
- Anja Declercq,
- Mark Hoogendoorn,
- Caitlin McArthur,
- Mari Aaltonen,
- Yi Chai,
- Karlijn J Joling,
- Micaela Jantzi,
- Rosa Liperoti,
- Melissa Northwood,
- Ilona Barańska,
- Agata Stodolska,
- Margaret Saari,
- Luca Mariotti,
- Emiel O Hoogendijk,
- Luke Turcotte,
- Louk Smalbil,
- Elizabeth P Howard,
- John N Morris,
- Daniela Fialová,
- Eline CM Kooijmans,
- Riikka-Leena Leskelä,
- Jokke Häsä,
- Georg Ruppe,
- Hein PJ van Hout,
- Carmen Angioletti,
- Olena Antonenko,
- Shireen Aziz,
- Gustavo Betini,
- Jovana Brkič,
- Roberto Da Cas,
- Daniel Da Cunha Leme,
- Lu Dai,
- Cecilia Damiano,
- Natalia Drapała,
- Bonaventure Egbujie,
- Collin JC Exmann,
- Harriet Finne-Soveri,
- Charlene France,
- Tiziana Grisetti,
- Ira Haavisto,
- Sophie Hogeveen,
- Paweł Jagielski,
- Laurian Jongejan,
- Jet E Klunder,
- Ingrid Kummer,
- Anna Lukačišinová,
- Matti Mäkelä,
- Krista Mathias,
- Amanda Mofina,
- Reem Mulla,
- Mikko Nuutinen,
- Sandra Ochwat,
- Paula Pennanen,
- Jitka Pokladníková,
- Bregtje Proost,
- Ahmer Raza,
- Emanuele Rocco Villani,
- Jindra Reissigová,
- Erez Schachter,
- Katarzyna Sekulak,
- Chi-Ling Joanna Sinn,
- Andrea Vokálová,
- Adrianna Ziuziakowska
Affiliations
- John P Hirdes
- School of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada
- Hao Luo
- Exercise Medicine Research Institute, Edith Cowan University, Joondalup, Western Australia, Australia
- Davide L Vetrano
- 1 Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
- Graziano Onder
- Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanita’, Rome, Italy
- Jonathan Chen
- 1 Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
- Violetta Kijowska
- 7 Department of Sociology of Medicine, Medical Faculty, Jagiellonian University Medical College, Krakow, Poland
- Katarzyna Szczerbińska
- Sociology of Medicine, Jagiellonian University Medical College Faculty of Medicine, Krakow, Poland
- Johanna Edgren
- 1 Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
- Amaia Calderón-Larrañaga
- 1 Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden
- George Heckman
- Schlegel-UW Research Institute for Aging, Waterloo, Ontario, Canada
- Ron MC Herings
- PHARMO Institute, PHARMO Institute for Drug Outcomes Research, Utrecht, The Netherlands
- Johanna de Almeida Mello
- Centre for Care Research & Consultancy(LUCAS), KU Leuven, Leuven, Belgium
- Anja Declercq
- LUCAS Centre for Care Research and Consultancy, KU Leuven, Leuven, Belgium
- Mark Hoogendoorn
- Department of Computer Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
- Caitlin McArthur
- School of Physiotherapy, Dalhousie University, Halifax, Nova Scotia, Canada
- Mari Aaltonen
- Faculty of Social Sciences (Health Sciences) and Gerontology Research Center, University of Tampere, Tampere, Finland
- Yi Chai
- 1 Department of Systems Engineering and Engineering Management, City University of Hong Kong, Kowloon, Hong Kong SAR, China
- Karlijn J Joling
- Amsterdam Public Health research Institute, Department of Medicine for Older People, Amsterdam UMC, VUmc site, Amsterdam, Netherlands
- Micaela Jantzi
- School of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada
- Rosa Liperoti
- Centro di Medicina dell’Invecchiamento, Dipartimento di Scienze >Gerontologiche, Geriatriche e Fisiatriche, Università Cattolica del Sacro >Cuore, Rome, Italy
- Melissa Northwood
- Nurse Continence Advisor St Peter’s Hospital Hamilton, Ontario, Canada
- Ilona Barańska
- Agata Stodolska
- Margaret Saari
- SE Research Centre, SE Health, Markham, Ontario, Canada
- Luca Mariotti
- project manager
- Emiel O Hoogendijk
- Department of Epidemiology & Data Science, Amsterdam Public Health research institute, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands
- Luke Turcotte
- University of Waterloo, Waterloo, Ontario, Canada
- Louk Smalbil
- Department of Computer Science, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
- Elizabeth P Howard
- Connell School of Nursing, Boston College, Chestnut Hill, Boston, MA, USA
- John N Morris
- The Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA
- Daniela Fialová
- Department of Social and Clinical Pharmacy, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic
- Eline CM Kooijmans
- Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of General Practice, De Boelelaan 1117, Amsterdam, The Netherlands
- Riikka-Leena Leskelä
- Nordic Healthcare Group, Helsinki, Finland
- Jokke Häsä
- Data and Analytics Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
- Georg Ruppe
- European Geriatric Medicine Society (EUGMS), Vienna, Austria
- Hein PJ van Hout
- Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of General Practice, De Boelelaan 1117, Amsterdam, The Netherlands
- Carmen Angioletti
- Olena Antonenko
- Shireen Aziz
- Gustavo Betini
- Jovana Brkič
- Roberto Da Cas
- Daniel Da Cunha Leme
- Lu Dai
- Cecilia Damiano
- Natalia Drapała
- Bonaventure Egbujie
- Collin JC Exmann
- Harriet Finne-Soveri
- Charlene France
- Tiziana Grisetti
- Ira Haavisto
- Sophie Hogeveen
- Paweł Jagielski
- Laurian Jongejan
- Jet E Klunder
- Ingrid Kummer
- Anna Lukačišinová
- Matti Mäkelä
- Krista Mathias
- Amanda Mofina
- Reem Mulla
- Mikko Nuutinen
- Sandra Ochwat
- Paula Pennanen
- Jitka Pokladníková
- Bregtje Proost
- Ahmer Raza
- Emanuele Rocco Villani
- Jindra Reissigová
- Erez Schachter
- Katarzyna Sekulak
- Chi-Ling Joanna Sinn
- Andrea Vokálová
- Adrianna Ziuziakowska
- DOI
- https://doi.org/10.1136/bmjopen-2023-072399
- Journal volume & issue
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Vol. 13,
no. 6
Abstract
Introduction In ageing societies, the number of older adults with complex chronic conditions (CCCs) is rapidly increasing. Care for older persons with CCCs is challenging, due to interactions between multiple conditions and their treatments. In home care and nursing homes, where most older persons with CCCs receive care, professionals often lack appropriate decision support suitable and sufficient to address the medical and functional complexity of persons with CCCs. This EU-funded project aims to develop decision support systems using high-quality, internationally standardised, routine care data to support better prognostication of health trajectories and treatment impact among older persons with CCCs.Methods and analysis Real-world data from older persons aged ≥60 years in home care and nursing homes, based on routinely performed comprehensive geriatric assessments using interRAI systems collected in the past 20 years, will be linked with administrative repositories on mortality and care use. These include potentially up to 51 million care recipients from eight countries: Italy, the Netherlands, Finland, Belgium, Canada, USA, Hong Kong and New Zealand. Prognostic algorithms will be developed and validated to better predict various health outcomes. In addition, the modifying impact of pharmacological and non-pharmacological interventions will be examined. A variety of analytical methods will be used, including techniques from the field of artificial intelligence such as machine learning. Based on the results, decision support tools will be developed and pilot tested among health professionals working in home care and nursing homes.Ethics and dissemination The study was approved by authorised medical ethical committees in each of the participating countries, and will comply with both local and EU legislation. Study findings will be shared with relevant stakeholders, including publications in peer-reviewed journals and presentations at national and international meetings.
