Nature Communications (May 2020)

Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0

  • Francesco Asnicar,
  • Andrew Maltez Thomas,
  • Francesco Beghini,
  • Claudia Mengoni,
  • Serena Manara,
  • Paolo Manghi,
  • Qiyun Zhu,
  • Mattia Bolzan,
  • Fabio Cumbo,
  • Uyen May,
  • Jon G. Sanders,
  • Moreno Zolfo,
  • Evguenia Kopylova,
  • Edoardo Pasolli,
  • Rob Knight,
  • Siavash Mirarab,
  • Curtis Huttenhower,
  • Nicola Segata

DOI
https://doi.org/10.1038/s41467-020-16366-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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The increasing amount of sequenced microbial genomes and metagenomes requires platforms for efficient integrated analysis. Here, Asnicar et al. present PhyloPhlAn 3.0, a pipeline allowing large-scale microbial genome characterization and phylogenetic contextualization at multiple levels of resolution.