Nature Communications (May 2020)
Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0
- Francesco Asnicar,
- Andrew Maltez Thomas,
- Francesco Beghini,
- Claudia Mengoni,
- Serena Manara,
- Paolo Manghi,
- Qiyun Zhu,
- Mattia Bolzan,
- Fabio Cumbo,
- Uyen May,
- Jon G. Sanders,
- Moreno Zolfo,
- Evguenia Kopylova,
- Edoardo Pasolli,
- Rob Knight,
- Siavash Mirarab,
- Curtis Huttenhower,
- Nicola Segata
Affiliations
- Francesco Asnicar
- Department CIBIO, University of Trento
- Andrew Maltez Thomas
- Department CIBIO, University of Trento
- Francesco Beghini
- Department CIBIO, University of Trento
- Claudia Mengoni
- Department CIBIO, University of Trento
- Serena Manara
- Department CIBIO, University of Trento
- Paolo Manghi
- Department CIBIO, University of Trento
- Qiyun Zhu
- Department of Pediatrics, University of California San Diego
- Mattia Bolzan
- Department CIBIO, University of Trento
- Fabio Cumbo
- Department CIBIO, University of Trento
- Uyen May
- Department of Electrical and Computer Engineering, University of California San Diego
- Jon G. Sanders
- Department of Pediatrics, University of California San Diego
- Moreno Zolfo
- Department CIBIO, University of Trento
- Evguenia Kopylova
- Department of Pediatrics, University of California San Diego
- Edoardo Pasolli
- Department CIBIO, University of Trento
- Rob Knight
- Department of Pediatrics, University of California San Diego
- Siavash Mirarab
- Department of Electrical and Computer Engineering, University of California San Diego
- Curtis Huttenhower
- Department of Biostatistics, Harvard T. H. Chan School of Public Health
- Nicola Segata
- Department CIBIO, University of Trento
- DOI
- https://doi.org/10.1038/s41467-020-16366-7
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 10
Abstract
The increasing amount of sequenced microbial genomes and metagenomes requires platforms for efficient integrated analysis. Here, Asnicar et al. present PhyloPhlAn 3.0, a pipeline allowing large-scale microbial genome characterization and phylogenetic contextualization at multiple levels of resolution.