An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms

• Simon Mitchell,
• Ellen L. Mercado,
• Adewunmi Adelaja,
• Jessica Q. Ho,
• Quen J. Cheng,
• Gourisankar Ghosh,
• Alexander Hoffmann,
• Alexander Hoffmann

Affiliations

Simon Mitchell

Signaling Systems Laboratory, Institute for Quantitative and Computational Biosciences, Department of Microbiology, Immunology, and Molecular Genetics, and Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States

Ellen L. Mercado

Signaling Systems Laboratory, San Diego Center for Systems Biology, La Jolla, CA, United States

Adewunmi Adelaja

Signaling Systems Laboratory, Institute for Quantitative and Computational Biosciences, Department of Microbiology, Immunology, and Molecular Genetics, and Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States

Jessica Q. Ho

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States

Quen J. Cheng

Signaling Systems Laboratory, Institute for Quantitative and Computational Biosciences, Department of Microbiology, Immunology, and Molecular Genetics, and Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States

Gourisankar Ghosh

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States

Alexander Hoffmann

Signaling Systems Laboratory, Institute for Quantitative and Computational Biosciences, Department of Microbiology, Immunology, and Molecular Genetics, and Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States

Alexander Hoffmann

Signaling Systems Laboratory, San Diego Center for Systems Biology, La Jolla, CA, United States