1002 Single cell transcriptomics in kidney tissue from African American patients enrolled in the accelerating medicines partnership (AMP) implicates tubular cells in the pathogenesis of APOL1 associated lupus nephritis

• Richard Furie,
• Brad Rovin,
• Michelle Petri,
• Judith A James,
• Kenneth Kalunian,
• Maria Dall’Era,
• Jill Buyon,
• Chaim Putterman,
• Peter Izmirly,
• Betty Diamond,
• David Wofsy,
• Ming Wu,
• Soumya Raychaudhuri,
• Philip M Carlucci,
• Qian Xiao,
• Nir Hacohen,
• Jennifer Anolik,
• H Michael Belmont,
• Robert Clancy,
• Kelly Ruggles,
• ANNE DAVIDSON,
• Deepak Rao,
• Celine C Berthier,
• Andrea Fava,
• Diane Kamen,
• Joel Guthridge,
• Arnon Arazi,
• Jose Monroy-Trujillo,
• Kristin Haag,
• William Apruzzese,
• Fernanda Payan-Schober,
• Kerry Cho,
• Joseph Mears,
• Wade DeJager,
• Paul Hoover,
• Kristina Deonaraine,
• Siddarth Gurajala,
• Derek Fine,
• Devyn Zaminski,
• Jasmine Shwetar,
• Katie Preisinger,
• Sethu Madhavan

Affiliations

Richard Furie

7Hofstra Northwell School of Medicine, New York, NY, United States of America

Brad Rovin

Department of Internal Medicine–Nephrology, The Ohio State University, Columbus, Ohio, USA

Michelle Petri

16 Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Judith A James

8 Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA

Kenneth Kalunian

9University of California, San Diego, La Jolla, United States of America

Maria Dall’Era

14Ohio State University, Columbus OH, United States of America

Jill Buyon

6Rheumatology, NYU Grossman School of Medicine, USA

Chaim Putterman

Division of Rheumatology and Department of Microbiology and Immunology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA

Peter Izmirly

2 Rheumatology, NYU Grossman School of Medicine, New York City, New York, USA

Betty Diamond

8The Feinstein Institute for Medical Research, Manhasset, United States of America

David Wofsy

7UCSF Medical Center, San Francisco, United States of America

Ming Wu

1 Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China

Soumya Raychaudhuri

University of Manchester, Arthritis Research UK Centre for Genetics and Genomics, Manchester, United Kingdom

Philip M Carlucci

Division of Rheumatology, New York University Grossman School of Medicine, New York, NY, USA

Qian Xiao

2 Mental Health Center of Xiangya Hospital, Central South University, Changsha, Hunan, China

Nir Hacohen

3Harvard Medical School, Boston, United States of America

Jennifer Anolik

Department of Medicine, Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, USA

H Michael Belmont

1New York University School of Medicine, USA

Robert Clancy

1NYU Langone Health, USA

Kelly Ruggles

Institute for Systems Genetics, NYU Langone Health, New York City, New York, USA

ANNE DAVIDSON

8The Feinstein Institute for Medical Research, Manhasset, United States of America

Deepak Rao

3Harvard Medical School, Boston, United States of America

Celine C Berthier

Internal Medicine, Department of Nephrology, University of Michigan, Ann Arbor, MI, USA

Andrea Fava

1Johns Hopkins University, Baltimore, United States of America

Diane Kamen

6Department of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA

Joel Guthridge

1Oklahoma Medical Research Foundation, Arthritis and Clinical Immunology, Oklahoma City, United States of America

Arnon Arazi

4Broad Institute, Cambridge, United States of America

Jose Monroy-Trujillo

11Nephrology, Johns Hopkins University, USA

Kristin Haag

Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA

William Apruzzese

9Division of Rheumatology, Immunology, Allergy, Department of Medicine, Brigham and Women’s Hospital, Boston, USA

Fernanda Payan-Schober

Department of Internal Medicine, Paul L Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA

Kerry Cho

Nephrology Division, University of California San Francisco, San Francisco, CA, USA

Joseph Mears

2Brigham and Women’s Hospital, USA

Wade DeJager

Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

Paul Hoover

17Broad Institute, Broad Institute, USA

Kristina Deonaraine

2University at Buffalo, USA

Siddarth Gurajala

2Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Derek Fine

11Nephrology, Johns Hopkins University, USA

Devyn Zaminski

1 NYU Grossman School of Medicine, New York City, New York, USA

Jasmine Shwetar

1NYU Grossman School of Medicine, USA

Katie Preisinger

1NYU Grossman School of Medicine, USA

Sethu Madhavan

5The Ohio State University, USA