Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies

• Yossa Dwi Hartono,
• Y. Vladimir Pabon-Martinez,
• Arzu Uyar,
• Jesper Wengel,
• Karin E. Lundin,
• Rula Zain,
• C. I. Edvard Smith,
• Lennart Nilsson,
• Alessandra Villa

Affiliations

Yossa Dwi Hartono

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

Y. Vladimir Pabon-Martinez

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Huddinge, Sweden

Arzu Uyar

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

Jesper Wengel

Department of Physics, Chemistry and Pharmacy, Nucleic Acid Center, University of Southern Denmark, Odense M, Denmark

Karin E. Lundin

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Huddinge, Sweden

Rula Zain

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Huddinge, Sweden

C. I. Edvard Smith

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Huddinge, Sweden

Lennart Nilsson

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

Alessandra Villa

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden