Alveolar Echinococcosis in a Patient with Presumed Autoimmune Hepatitis and Primary Sclerosing Cholangitis: An Unexpected Finding after Liver Transplantation
Florian Fronhoffs,
Leona Dold,
Marijo Parčina,
Arne Schneidewind,
Maria Willis,
Thomas F. E. Barth,
Tobias J. Weismüller,
Taotao Zhou,
Philipp Lutz,
Julian A. Luetkens,
Peter Gerlach,
Steffen Manekeller,
Jörg C. Kalff,
Tim O. Vilz,
Christian P. Strassburg,
Glen Kristiansen
Affiliations
Florian Fronhoffs
Institute of Pathology, University Hospital Bonn (UKB), 53127 Bonn, Germany
Leona Dold
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Marijo Parčina
Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn (UKB), 53127 Bonn, Germany
Arne Schneidewind
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Maria Willis
Department of General, Visceral-, Thoracic and Vascular Surgery, University Hospital Bonn (UKB), 53127 Bonn, Germany
Thomas F. E. Barth
Institute of Pathology, Ulm University, 89081 Ulm, Germany
Tobias J. Weismüller
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Taotao Zhou
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Philipp Lutz
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Julian A. Luetkens
Department of Radiology, University of Bonn (UKB), 53127 Bonn, Germany
Peter Gerlach
Institute of Pathology, Bonn-Duisdorf, 53123 Bonn, Germany
Steffen Manekeller
Department of General, Visceral-, Thoracic and Vascular Surgery, University Hospital Bonn (UKB), 53127 Bonn, Germany
Jörg C. Kalff
Department of General, Visceral-, Thoracic and Vascular Surgery, University Hospital Bonn (UKB), 53127 Bonn, Germany
Tim O. Vilz
Department of General, Visceral-, Thoracic and Vascular Surgery, University Hospital Bonn (UKB), 53127 Bonn, Germany
Christian P. Strassburg
Department of Internal Medicine I, University Hospital Bonn (UKB), 53127 Bonn, Germany
Glen Kristiansen
Institute of Pathology, University Hospital Bonn (UKB), 53127 Bonn, Germany
Primary sclerosing cholangitis is an important reason for liver transplantation. Hepatic alveolar echinococcosis (AE) is caused by Echinococcus multilocularis and presents characteristic calcified conglomerates detected by ultrasound or computed tomography scan of the liver. Symptoms of AE only occur after a long period of infection when cholestasis or cholangitis becomes apparent. Here, we report on a patient with presumed autoimmune hepatitis and primary sclerosing cholangitis. After liver transplantation, alveolar echinococcosis was diagnosed in the liver explant.