Pathogens (Jan 2023)

Alveolar Echinococcosis in a Patient with Presumed Autoimmune Hepatitis and Primary Sclerosing Cholangitis: An Unexpected Finding after Liver Transplantation

  • Florian Fronhoffs,
  • Leona Dold,
  • Marijo Parčina,
  • Arne Schneidewind,
  • Maria Willis,
  • Thomas F. E. Barth,
  • Tobias J. Weismüller,
  • Taotao Zhou,
  • Philipp Lutz,
  • Julian A. Luetkens,
  • Peter Gerlach,
  • Steffen Manekeller,
  • Jörg C. Kalff,
  • Tim O. Vilz,
  • Christian P. Strassburg,
  • Glen Kristiansen

DOI
https://doi.org/10.3390/pathogens12010073
Journal volume & issue
Vol. 12, no. 1
p. 73

Abstract

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Primary sclerosing cholangitis is an important reason for liver transplantation. Hepatic alveolar echinococcosis (AE) is caused by Echinococcus multilocularis and presents characteristic calcified conglomerates detected by ultrasound or computed tomography scan of the liver. Symptoms of AE only occur after a long period of infection when cholestasis or cholangitis becomes apparent. Here, we report on a patient with presumed autoimmune hepatitis and primary sclerosing cholangitis. After liver transplantation, alveolar echinococcosis was diagnosed in the liver explant.

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