Nephrotic syndrome secondary to Sjögren syndrome in an older adult: a clinical case analysis

Abstract

We report an 80-year-old woman who was admitted to our geriatric unit with progressive symptoms of proteinuria, edema, and fatigue. The clinical presentation was caused by a nephrotic syndrome (NS) due to membranoproliferative glomerulonephritis secondary to Sjögren’s syndrome. Treatment with immunosuppressive drugs was initiated, which resulted in significant improvement in the patient’s clinical symptoms and laboratory findings. The case highlights the importance of an appropriate diagnostic approach to NS in older adults, and the need for prompt management to prevent further kidney damage and improve older patient clinical outcomes.

Keywords

• Nephrotic syndrome. Nephrogeriatrics. Membranoproliferative glomerulonephritis. Sjögren syndrome.