Nature Communications (Aug 2020)
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
- Jae-Hyung Jin,
- Kyung-Tae Lee,
- Joohyeon Hong,
- Dongpil Lee,
- Eun-Ha Jang,
- Jin-Young Kim,
- Yeonseon Lee,
- Seung-Heon Lee,
- Yee-Seul So,
- Kwang-Woo Jung,
- Dong-Gi Lee,
- Eunji Jeong,
- Minjae Lee,
- Yu-Byeong Jang,
- Yeseul Choi,
- Myung Ha Lee,
- Ji-Seok Kim,
- Seong-Ryong Yu,
- Jin-Tae Choi,
- Jae-Won La,
- Haneul Choi,
- Sun-Woo Kim,
- Kyung Jin Seo,
- Yelin Lee,
- Eun Jung Thak,
- Jaeyoung Choi,
- Anna F. Averette,
- Yong-Hwan Lee,
- Joseph Heitman,
- Hyun Ah Kang,
- Eunji Cheong,
- Yong-Sun Bahn
Affiliations
- Jae-Hyung Jin
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Kyung-Tae Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Joohyeon Hong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Dongpil Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Eun-Ha Jang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Jin-Young Kim
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yeonseon Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Seung-Heon Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yee-Seul So
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Kwang-Woo Jung
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Dong-Gi Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Eunji Jeong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Minjae Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yu-Byeong Jang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yeseul Choi
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Myung Ha Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Ji-Seok Kim
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Seong-Ryong Yu
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Jin-Tae Choi
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Jae-Won La
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Haneul Choi
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Sun-Woo Kim
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Kyung Jin Seo
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yelin Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Eun Jung Thak
- Department of Life Science, College of Natural Science, Chung-Ang University
- Jaeyoung Choi
- Smart Farm Research Center, Korea Institute of Science and Technology
- Anna F. Averette
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Yong-Hwan Lee
- Department of Agricultural Biotechnology, Seoul National University
- Joseph Heitman
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Hyun Ah Kang
- Department of Life Science, College of Natural Science, Chung-Ang University
- Eunji Cheong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yong-Sun Bahn
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- DOI
- https://doi.org/10.1038/s41467-020-18028-0
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 17
Abstract
Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.
