Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement

Zhengzhong Lin; Shengyang Chen; Lei Li; Aihong Peng; Zhiyong Huang

Heliyon (Oct 2020)

Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement

Zhengzhong Lin,
Shengyang Chen,
Lei Li,
Aihong Peng,
Zhiyong Huang

Affiliations

Zhengzhong Lin: College of Food and Biological Engineering, Jimei University, Xiamen, 361021, China; Corresponding author.
Shengyang Chen: College of Food and Biological Engineering, Jimei University, Xiamen, 361021, China; College of Biological Science and Engineering, Fuzhou University, Fujian Province, 350108, China
Lei Li: College of Food and Biological Engineering, Jimei University, Xiamen, 361021, China
Aihong Peng: College of Food and Biological Engineering, Jimei University, Xiamen, 361021, China
Zhiyong Huang: College of Food and Biological Engineering, Jimei University, Xiamen, 361021, China

Journal volume & issue: Vol. 6, no. 10
p. e05287

Abstract

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A magnetic molecularly imprinted silica solid was obtained by sol-gel polymerization for the separation of domoic acid. The solid showed rapid adsorption kinetics with an adsorption equilibrium time of 5 min. The solid showed affinity to domoic acid under the interference of tryptophan and could be repeatedly used for 5 times at least. The solid was used as a solid-phase-extraction sorbent for the extraction of domoic acid from clam samples before measurement with liquid chromatography. The detection limit of 0.20 mg kg−1 was lower than the allowable limits in several countries or areas. The recoveries in the spiked samples were 88% approximately.

Published in Heliyon

ISSN: 2405-8440 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Science (General); Social Sciences: Social sciences (General)
Website: https://www.cell.com/heliyon/home

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