Radiology Case Reports (Jan 2022)

Bilateral lacrimal gland lymphoma: Case report and literature review

  • Luu-Thi Bich Ngoc, MD,
  • Ngo-Van Doan, MD,
  • Vuong Kim Ngan, MD,
  • Nguyen-Van Phan, MD,
  • Nguyen Quynh Giang, MD,
  • Huynh-Thi Do Quyen, MD,
  • Nguyen Minh Duc, MD

Journal volume & issue
Vol. 17, no. 1
pp. 240 – 244

Abstract

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Ocular adnexal lymphoma accounts for approximately 1%-2% of non-Hodgkin lymphomas and 8% of extranodal lymphomas. Lacrimal gland lymphoma, especially bilateral lacrimal gland lymphoma, is rare, and imaging is often utilized to differentiate lacrimal lymphoma from other types of masses that involve the lacrimal gland and the fossa. We describe a 74-year-old male patient presenting with bilateral eye proptosis, lachrymose without pain, and no changes in eyesight. Brain-orbit magnetic resonance imaging revealed bilateral lacrimal fossa masses with regular contours, moderate enhancement, and restriction on diffusion imaging, consistent with a lymphoma diagnosis, which was confirmed by histopathological results. Positron emission tomography-computed tomography was used to determine lymphoma grading. MRI, especially diffusion imaging, can be useful for guiding clinicians in the diagnosis and differentiation of lacrimal gland lymphoma from other lesions.

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