Lipid-mediated activation of plasma membrane-localized deubiquitylating enzymes modulate endosomal trafficking

Abstract

The endocytic degradation of plasma membrane proteins can be modulated by deubiquitylating enzymes (DUBs). Here, the authors describe two plasma membrane localized Arabidopsis DUBs that can be activated by binding to anionic lipids and influence the endocytic transport of plasma membrane proteins.