EVALUATION THE LEVEL OF SEROTONIN AND THE ACTIVITY OF ACETYLCHOLINE ESTERASE IN SERA OF SOMEFEMALE WITH TYPE I DIABETES

Abstract

This research included the study of the level of serotonin concentration and the activity of Acetylcholine esterase and their relationship with diabetes type I compared with healthy people (control group). Some other biological variations has been studied accompanying such as the concentration of glucose, cholesterol, triglyceride, HDL,LDL,VLDL in women with type I diabetes compared to healthy..Blood samples have been taken from to women with type I diabetes (IDDM) who are diagnosed by doctors, specialists, ages ranged between 17-37 years. Included in the study (60) model of the blood serum of women with type I diabetes as well as the control group, which included (40) model of the blood serum of healthy women.The study showed a significant increase in the activity of Acetylcholine esterase and the not significant increase in the level of serotonin in women with diabetes type I, as well as a significant increase in the level of concentration of glucose, HbA1C, cholesterol, triglyceride, LDL,VLDL with diabetes compared with control.It also examined the correlation between the level of serotonin andAcetylcholine esterase and Biological Variations of patients with diabetes type I and the control group it was found a positive coloration between the activity of Acetylcholine esterase and the value of the BMI and the level of glucose, HbA1C, the level of triglycerides,andVLDL. While there was anegativecoloration between the level of serotonin, BMI, blood pressure, HDL, and there was a positive coloration between the level of serotonin and the concentration of cholesterol, triglycerides andVLDL