Dermatologica Sinica (Jun 2013)

Dermatopathic lymphadenitis in a patient with pemphigus vulgaris

  • Jen-Jung Cheng,
  • Han Chang,
  • Hung-Chun Shih,
  • Shiow-Jiuan Wey,
  • Yu-Ping Hsiao

DOI
https://doi.org/10.1016/j.dsi.2012.09.003
Journal volume & issue
Vol. 31, no. 2
pp. 86 – 89

Abstract

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Dermatopathic lymphadenitis (DL) is a reactive lymphoid hyperplasia that commonly involves the regional lymph nodes in patients with chronic dermatoses, such as exfoliative dermatitis, toxic-shock syndrome, pemphigus, psoriasis, eczema, and, in severe cases, mycosis fungoides. Diagnosis of DL depends on the histopathologic characteristics of paracortical T-zone expansion with melanin, hemosiderin, or lipid-laden macrophages. Lymphadenopathies in patients with chronic dermatoses may be due not only to infections or malignancy, but also to reactive disorders such as DL. We describe the case of a 31-year-old woman with pemphigus vulgaris who has characteristic manifestations of DL.

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