Oxcarbazepine-induced stevens johnson syndrome and toxic epidermal necrolysis overlap

Abstract

Drug-induced skin reactions are familiar with older epileptic drugs such as phenytoin, lamotrigine, and carbamazepine (CBZ); the newer antiepileptic drugs are less likely to cause. Oxcarbazepine (OXC), the successor of CBZ, has a better safety profile with respect to side effects and adverse drug reactions (ADRs). The StevensJohnson syndrome (SJS), an ADR, is less common with OXC, and there are few case reports in the literature. Here, we report a case of OXC-induced SJS/toxic epidermal necrolysis overlap in line with CARE guidelines.

Keywords

• adverse drug reaction
• oxcarbazepine
• skin reaction
• stevens–johnson syndrome
• toxic epidermal necrolysis