Nature Communications (Feb 2018)

Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation

  • Juliana Durack,
  • Nikole E. Kimes,
  • Din L. Lin,
  • Marcus Rauch,
  • Michelle McKean,
  • Kathryn McCauley,
  • Ariane R. Panzer,
  • Jordan S. Mar,
  • Michael D. Cabana,
  • Susan V. Lynch

DOI
https://doi.org/10.1038/s41467-018-03157-4
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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Gut microbial dysbiosis in infancy is associated with childhood atopy and the development of asthma. Here, the authors show that gut microbiota perturbation is evident in the very earliest stages of postnatal life, continues throughout infancy, and can be partially rescued by Lactobacillus supplementation in high-risk for asthma infants.