Van Tıp Dergisi (Oct 2022)

Ertapenem Related Neurotoxicity Presented with Visual Halusinations in Chronic Kidney Failure Patient

  • Seçkin Akben,
  • İlyas Öztürk,
  • Ertugrul Erken,
  • Özkan Güngör,
  • Orcun Altunören

DOI
https://doi.org/10.5505/vtd.2022.83356
Journal volume & issue
Vol. 29, no. 4
pp. 440 – 444

Abstract

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During the follow-up of patients with renal failure, many medications may be required due to the clinical condition and comorbidities. Care should be taken in terms of the nephrotoxic effect of these drugs used or the accumulation of renally excreted drugs in the body and causing toxic effects. One of the most important side effects of carbapenems is neurotoxicity. Although Imipenem is the most frequently mentioned in this respect, similar side effects can be seen due to other carbapenems. Even if the dose is adjusted according to the glomerular filtration rate, these side effects can be seen. When the literature is examined, it has been determined that neurotoxicity due to ertapenem is seen more frequently than expected. In this study, we wanted to draw attention to this issue by presenting our case of visual hallucination observed after the use of ertapenem in a patient with chronic renal failure.

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