Molecules (Apr 2024)

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol

  • Li Ma,
  • Mengke Liu,
  • Chuntong Liu,
  • Huachang Zhang,
  • Shude Yang,
  • Jing An,
  • Guiwu Qu,
  • Shuling Song,
  • Qizhi Cao

DOI
https://doi.org/10.3390/molecules29091943
Journal volume & issue
Vol. 29, no. 9
p. 1943

Abstract

Read online

Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors. CBD can exert its antitumor effect by regulating the cell cycle, inducing tumor cell apoptosis and autophagy, and inhibiting tumor cell invasion, migration, and angiogenesis. This article reviews the proposed antitumor mechanisms of CBD, aiming to provide references for the clinical treatment of tumor diseases and the rational use of CBD.

Keywords