Behavioural Neurology (Jan 2002)
Pergolide Mesilate May Improve Fatigue in Patients with Parkinson’s Disease
Abstract
Objectives: Fatigue is a complaint frequently encountered among patients with Parkinson’s disease (PD). Considering the possible relationship between fatigue and dopaminergic dysfuncion, we investigated the effect of pergolide mesilate (a D2 and D1 dopamine receptor agonist) and bromocriptine (a D2 selective dopamine receptor) in patients with PD.