Design and manufacturing of a patient-specific nasal implant for congenital arhinia: Case report
Alessandro Borghi,
Federica Ruggiero,
Maik Tenhagen,
Silvia Schievano,
Allan Ponniah,
David Dunaway,
Justine O'Hara,
Juling Ong,
Jonathan A. Britto
Affiliations
Alessandro Borghi
Developmental Biology and Cancer Programme, Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK; Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK; Corresponding author at: Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.
Federica Ruggiero
Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Maik Tenhagen
Developmental Biology and Cancer Programme, Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK; Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Silvia Schievano
Developmental Biology and Cancer Programme, Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK; Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Allan Ponniah
Department of Plastic Surgery, Royal Free Hospital, Pond Street, London NW3 2QG. UK
David Dunaway
Developmental Biology and Cancer Programme, Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK; Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Justine O'Hara
Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Juling Ong
Craniofacial Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 1JH, UK
Arhinia (congenital absence of the nose) is a congenital rare disease, which has been reported in less than 60 cases in the literature. It consists of the absence of external nose, nasal cavities and olfactory apparatus and is generally associated with midline defects, microphthalmia, blepharophimosis and hypotelorism. Aesthetic problems as well as associated functional anomalies can potentially impact on the development and interpersonal relationships of the child at a later stage in life.Arhinia requires extensive management in early life in order to ensure airway patency and protection by means of tracheostomy, and to allow adequate pharyngeal and feeding function to the child. Aesthetic issues are managed with reconstructive surgery or an external prosthesis. There is no previous description in Literature of internal prosthetic devices used to sequentially shape soft tissues in complex reconstruction.We present an example of design and manufacturing of a bespoke nose implant produced by means of 3D printing and directly assessed on-table by means of 3D surface scanning. Keywords: Congenital arhinia, 3D priting, 3D scanning, Patient specific implant
