A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

Hongzhong Lu; Feiran Li; Benjamín J. Sánchez; Zhengming Zhu; Gang Li; Iván Domenzain; Simonas Marcišauskas; Petre Mihail Anton; Dimitra Lappa; Christian Lieven; Moritz Emanuel Beber; Nikolaus Sonnenschein; Eduard J. Kerkhoven; Jens Nielsen

doi:10.1038/s41467-019-11581-3

Nature Communications (Aug 2019)

A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

Hongzhong Lu,
Feiran Li,
Benjamín J. Sánchez,
Zhengming Zhu,
Gang Li,
Iván Domenzain,
Simonas Marcišauskas,
Petre Mihail Anton,
Dimitra Lappa,
Christian Lieven,
Moritz Emanuel Beber,
Nikolaus Sonnenschein,
Eduard J. Kerkhoven,
Jens Nielsen

Affiliations

Hongzhong Lu: Department of Biology and Biological Engineering, Chalmers University of Technology
Feiran Li: Department of Biology and Biological Engineering, Chalmers University of Technology
Benjamín J. Sánchez: Department of Biology and Biological Engineering, Chalmers University of Technology
Zhengming Zhu: Department of Biology and Biological Engineering, Chalmers University of Technology
Gang Li: Department of Biology and Biological Engineering, Chalmers University of Technology
Iván Domenzain: Department of Biology and Biological Engineering, Chalmers University of Technology
Simonas Marcišauskas: Department of Biology and Biological Engineering, Chalmers University of Technology
Petre Mihail Anton: Department of Biology and Biological Engineering, Chalmers University of Technology
Dimitra Lappa: Department of Biology and Biological Engineering, Chalmers University of Technology
Christian Lieven: The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Moritz Emanuel Beber: The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Nikolaus Sonnenschein: The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Eduard J. Kerkhoven: Department of Biology and Biological Engineering, Chalmers University of Technology
Jens Nielsen: Department of Biology and Biological Engineering, Chalmers University of Technology

DOI: https://doi.org/10.1038/s41467-019-11581-3
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 13

Abstract

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Genome-scale metabolic models provide a platform to study metabolism through simulations and analysis of omics data. Here the authors introduce Yeast8 with its model ecosystem, a comprehensive computational resource for simulating the metabolism of Saccharomyces cerevisiae.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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