Brazilian Journal of Infectious Diseases (Sep 2018)

Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center

  • Karla Maria Tamez-Torres,
  • Pedro Torres-Gonzalez,
  • Miguel E. Cervera-Hernandez,
  • Barbara Chavez-Mazari,
  • Corazon de Jesus Barrientos-Flores,
  • Miriam Bobadilla-del-Valle,
  • Alfredo Ponce-de-Leon,
  • Jose Sifuentes-Osornio

Journal volume & issue
Vol. 22, no. 5
pp. 387 – 391

Abstract

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Objectives: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture. Methods: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. Results: We reviewed medical records of 533 patients with culture-proven tuberculosis, of whom 27.2% (145/533) had blood culture available. Patients with mycobacteremia presented more frequently with abdominal tuberculosis, body mass index <18 kg/m2, and had lower hemoglobin and albumin levels. No differences were observed regarding HIV status. Conclusions: Few studies have reported on the characteristics associated with Mycobacterium tuberculosis complex bacteremia, especially among Human Immunodeficiency Virus-negative patients. Out of 145 tuberculosis-infected patients with blood culture results available, 21 turned out positive. Anemia, hypoalbuminemia, and a body mass index < 18 kg/m2 were associated with mycobacteremia. Keywords: Mycobacterium tuberculosis, Human immunodeficiency virus, Bloodstream infection, Mycobacteremia, Case-control study