Longitudinal changes in adiposity following anterior cruciate ligament reconstruction and associations with knee symptoms and function

Amélie Michaud; Chris Koskoletos; Brooke E. Patterson; Kay M. Crossley; Trevor B. Birmingham; Adam G. Culvenor; Harvi F. Hart

Osteoarthritis and Cartilage Open (Jun 2024)

Longitudinal changes in adiposity following anterior cruciate ligament reconstruction and associations with knee symptoms and function

Amélie Michaud,
Chris Koskoletos,
Brooke E. Patterson,
Kay M. Crossley,
Trevor B. Birmingham,
Adam G. Culvenor,
Harvi F. Hart

Affiliations

Amélie Michaud: Action Sport Physio, Sherbrooke, Canada; School of Physical Therapy, Western University, London, Canada
Chris Koskoletos: Rewind Physio, Embrun, Ontario, Canada; School of Physical Therapy, Western University, London, Canada
Brooke E. Patterson: La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora, Australia
Kay M. Crossley: La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora, Australia
Trevor B. Birmingham: School of Physical Therapy, Western University, London, Canada
Adam G. Culvenor: La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora, Australia
Harvi F. Hart: La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora, Australia; School of Physical Therapy, Western University, London, Canada; Corresponding author. School of Physical Therapy, Western University, 1151 Richmond Street, London, Ontario, Canada.

Journal volume & issue: Vol. 6, no. 2
p. 100473

Abstract

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Objective: To evaluate adiposity after anterior cruciate ligament reconstruction (ACLR): i) cross-sectionally (1-year post-ACLR) compared to uninjured controls; ii) longitudinally up to 5 years post-ACLR; and iii) associations with patient-reported symptoms and physical performance. Methods: In 107 individuals post-ACLR and 19 controls, we assessed global (BMI), peripheral (subcutaneous adipose tissue thickness on the posteromedial side of knee MRI), and central (waist circumference in ACLR group) adiposity. Patient-reported symptoms (Knee injury and Osteoarthritis Outcome Score) and physical performance (hop for distance) were evaluated at 1 and 5 years post-ACLR. Linear regression models evaluated adiposity between groups. Paired t-tests evaluated changes in adiposity from 1- to 5 years post-ACLR. Linear regression models analyzed adiposity's associations with patient-reported symptoms and physical performance at 1-year post-ACLR, changes in symptoms and performance over 4 years post-ACLR, and longitudinal changes in adiposity and symptoms and performance, controlling for age, sex, and activity level. Results: Individuals 1-year post-ACLR were associated with higher average global (3 kg/m2) and peripheral adiposity (2.3 mm). From 1- to 5 years post-ACLR, higher average global (0.58 kg/m2) and central (5 cm) adiposity, and lower average peripheral adiposity (1.3 mm) were observed. In general, adiposity at one-year post-ACLR was negatively associated with patient-reported symptoms and physical performance, and changes from 1 to 5 years post-ACLR. Increases in adiposity were negatively associated with changes in patient-reported symptoms and physical performance over four years post-ACLR. Conclusion: Greater global and central adiposity is a feature of young adults following ACLR and influences current and future patient-reported symptoms and physical performance.

Published in Osteoarthritis and Cartilage Open

ISSN: 2665-9131 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the musculoskeletal system
Website: https://www.journals.elsevier.com/osteoarthritis-and-cartilage-open/

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