Preventive effect of silver nanowires (Ag NWs) on oral implant repair infection

Abstract

Abstract The silver nanowires with different morphology and size have been synthesised via the one‐step solvothermal synthesis method. Three as‐synthesised samples 1–3 with different size have been obtained by changing the crystallisation time of the silver wire. The synthesised strategies for 1–3 provide us with new synthesised methods in designing and obtaining the silver nanowires with desired morphology. For the treatment of oral implant repair infection, the biological activity of silver nanowires 1–3 was evaluated, and the related mechanism was discussed at the same time. Firstly, the CFU assay was conducted to measure the inhibitory activity of silver nanowires 1–3 on the survival of Porphyromonas periodontium. Then, the real time RT‐PCR assay was performed and the relative expression of Porphyromonas periodontium survival gene expression was measured after silver nanowires 1–3 treatment. The CCK‐8 assay was conducted to measure the toxicity of the silver nanowires 1–3.