International Journal of General Medicine (Dec 2021)

Does Red Cell Distribution Width Predict Hip Fracture Mortality Among the Arab Population? A Single-Center Retrospective Cohort Study

  • Hamdan M,
  • Haddad BI,
  • Jabaiti M,
  • Alryalat SA,
  • Abdulelah AA,
  • Alabed SH,
  • Alabdullah TF,
  • Aouant AN,
  • Shahein HE,
  • Dweik HI,
  • Matar‎ K,
  • Alisi MS

Journal volume & issue
Vol. Volume 14
pp. 10195 – 10202

Abstract

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Mohammad Hamdan,1 Bassem I Haddad,1 Mohammad Jabaiti,1 Saif Aldeen Alryalat,2 Ahmed A Abdulelah,3 Shahed H Alabed,3 Tamadur F Alabdullah,3 Alia N Aouant,3 Haneen E Shahein,3 Hadeel I Dweik,3 Khaled Matar‎,4 Mohammed S Alisi1,5 1Department of Special Surgery, Division of Orthopaedics, School of Medicine, The University of Jordan, Amman, Jordan; 2Department of Special Surgery, Division of Ophthalmology, School of Medicine, The University of Jordan, Amman, Jordan; 3School of Medicine, The University of Jordan, Amman, Jordan; 4School of Medicine, American University of the Caribbean, Cupecoy, Sint Maarten; 5Faculty of Medicine, Islamic University of Gaza, Gaza, PalestineCorrespondence: Mohammed S AlisiSchool of Medicine, The University of Jordan, Queen Rania Al Abdullah St 266 Al Jubaiha, Amman, 11942, JordanTel +962790983284Email [email protected]: Hip fractures impose significant morbidity and mortality. Red cell distribution width (RDW) appears to be an emerging tool in predicting mortality following hip fractures. Several factors can influence the RDW value including genetic factors and ethnicity. The purpose of the study was to assess the relation between RDW level at admission and hip fracture mortality within 6 months among Arab/Middle East populations.Methods: We conducted a single-center retrospective cohort study including 549 patients (274 female and 275 male) diagnosed with a hip fracture undergoing surgery from February 2016 to December 2019. All included patients shared the same country of origin which is Arab Middle East country. Statistical analysis, including binary regression, was performed to assess the relationship between RDW and mortality within 6 months of admission. Other predictors of mortality following hip fracture surgery were also assessed.Results: The mean age was 76.42 (± 9.19) years. Seventy (12.8%) of participants died within 6 months. No statistically significant association (P=0.053) between RDW level at admission and mortality within 6 months of surgery was found. Binary regression demonstrated that the only independent predictors of mortality were age (P= 0.003, odds ratio 1.048 with 95% CI 1.016 to 1.080) and male gender (P= 0.021, odds ratio 1.872 with 95% CI 1.100 to 3.185).Conclusion: Although the previous studies reported that RDW is one of the predictors of mortality in hip fracture patients, our study found no relation in the Arab population. This finding may confirm the influence of genetic factors and ethnicity on RDW value. We recommend further large-scale multicenter studies to solidly establish the relationship between RDW and hip fracture mortality among the Arab/Middle East population.Keywords: RDW, hip fracture, mortality, Arab, red cell distribution width

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