mSphere (Apr 2021)
Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts
- Robert H. Bortz,
- Catalina Florez,
- Ethan Laudermilch,
- Ariel S. Wirchnianski,
- Gorka Lasso,
- Ryan J. Malonis,
- George I. Georgiev,
- Olivia Vergnolle,
- Natalia G. Herrera,
- Nicholas C. Morano,
- Sean T. Campbell,
- Erika P. Orner,
- Amanda Mengotto,
- M. Eugenia Dieterle,
- J. Maximilian Fels,
- Denise Haslwanter,
- Rohit K. Jangra,
- Alev Celikgil,
- Duncan Kimmel,
- James H. Lee,
- Margarette C. Mariano,
- Antonio Nakouzi,
- Jose Quiroz,
- Johanna Rivera,
- Wendy A. Szymczak,
- Karen Tong,
- Jason Barnhill,
- Mattias N. E. Forsell,
- Clas Ahlm,
- Daniel T. Stein,
- Liise-anne Pirofski,
- D. Yitzchak Goldstein,
- Scott J. Garforth,
- Steven C. Almo,
- Johanna P. Daily,
- Michael B. Prystowsky,
- James D. Faix,
- Amy S. Fox,
- Louis M. Weiss,
- Jonathan R. Lai,
- Kartik Chandran
Affiliations
- Robert H. Bortz
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Catalina Florez
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Ethan Laudermilch
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Ariel S. Wirchnianski
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Gorka Lasso
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Ryan J. Malonis
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- George I. Georgiev
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Olivia Vergnolle
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Natalia G. Herrera
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Nicholas C. Morano
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Sean T. Campbell
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Erika P. Orner
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Amanda Mengotto
- Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
- M. Eugenia Dieterle
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- J. Maximilian Fels
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Denise Haslwanter
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Rohit K. Jangra
- ORCiD
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Alev Celikgil
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Duncan Kimmel
- Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
- James H. Lee
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Margarette C. Mariano
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Antonio Nakouzi
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Jose Quiroz
- Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
- Johanna Rivera
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Wendy A. Szymczak
- ORCiD
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Karen Tong
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Jason Barnhill
- Department of Chemistry and Life Science, United States Military Academy at West Point, West Point, New York, USA
- Mattias N. E. Forsell
- ORCiD
- Department of Clinical Microbiology, Umeå University, Umeå, Sweden
- Clas Ahlm
- Department of Clinical Microbiology, Umeå University, Umeå, Sweden
- Daniel T. Stein
- Montefiore Medical Center, Bronx, New York, USA
- Liise-anne Pirofski
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- D. Yitzchak Goldstein
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Scott J. Garforth
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Steven C. Almo
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Johanna P. Daily
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- Michael B. Prystowsky
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- James D. Faix
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Amy S. Fox
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Louis M. Weiss
- ORCiD
- Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
- Jonathan R. Lai
- Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA
- Kartik Chandran
- ORCiD
- Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
- DOI
- https://doi.org/10.1128/mSphere.00224-21
- Journal volume & issue
-
Vol. 6,
no. 2
Abstract
Serological surveillance has become an important public health tool during the COVID-19 pandemic. Detection of protective antibodies and seroconversion after SARS-CoV-2 infection or vaccination can help guide patient care plans and public health policies.
