E3S Web of Conferences (Jan 2020)

Modern concepts of the fibrinolytic system

  • Sorokin Sergei,
  • Shamtsyan Mark,
  • Petrishchev Nicolai

DOI
https://doi.org/10.1051/e3sconf/202021505002
Journal volume & issue
Vol. 215
p. 05002

Abstract

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Among all medical pathologies, cardiovascular diseases are the most dangerous and deadly. On the one hand, thrombosis is a natural reaction of a person to damage to blood vessels, on the other hand, thrombosis is often the cause of death in the event of cardiovascular disease. There is a natural process called fibrinolysis to dissolve a blood clot after the bleeding has stopped and preventing vascular occlusion. This article examines current understanding of the human fibrinolytic system, main elements of fibrinolytic system and also addresses the topic of thrombolytic therapy.