ESC Heart Failure (Oct 2024)

Early achievement of walkability after cardiac surgery and the risk of cardiovascular disease after hospital discharge

  • Tomonori Kawamura,
  • Ryoto Sakaniwa,
  • Masato Nishimura,
  • Yoshimi Matsuo,
  • Yoshihide Imai,
  • Yusuke Hori,
  • Tomohumi Tsukizawa,
  • Keisuke Fukuda,
  • Makoto Matsuura,
  • Tetsushi Takemoto,
  • Oniti Furuya,
  • Satoshi Kuroyanagi,
  • Shiniti Higashiue,
  • Hiroyasu Iso,
  • Tomotaka Sobue

DOI
https://doi.org/10.1002/ehf2.14875
Journal volume & issue
Vol. 11, no. 5
pp. 3033 – 3040

Abstract

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Abstract Aims This study aimed to investigate the association between the time to achieve walkability after cardiac surgery and the risk of cardiovascular disease after hospital discharge. Methods We conducted a prospective cohort study involving 553 ambulatory patients aged 71.5 (range, 64.0–77.0) years who underwent cardiac surgery. All patients were divided into five groups based on the time to achieve walkability ≥100 m within 1, 2, 3, 4 or 5 days after cardiac surgery. We examined the risk of post‐cardiovascular disease outcomes, including readmission due to heart failure, ischaemic heart disease and other cardiovascular disease, according to the time to achieve walkability with reference to 5 days using the Fine and Gray regression model, considering competing risks. Results In the survival curve analysis, we examined the time to experience post‐cardiovascular disease incidence after hospital discharge. During a median of 3.3 years of follow‐up, 118 patients developed cardiovascular disease. We observed a positive association between the time to achieve walkability and cardiovascular disease risk, particularly heart failure. The multivariate hazard ratios (95% confidence intervals) for heart failure readmission were N/A (not assessed due to the sample size being too small) for 1 day, 0.31 (0.10–0.99) for 2 days, 0.60 (0.21–1.79) for 3 days and 0.76 (0.22–2.72) for 4 days (P for trend = 0.032). Conclusions The shorter walkability achievement time was associated with a lower risk of cardiovascular diseases, more specifically heart failure readmission, among patients who underwent cardiac surgery. The time required to achieve walkability is a useful predictor for cardiovascular diseases after hospital discharge.

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