Electric Field: A Key Signal in Wound Healing

Naixin JIA; Jinrui YANG; Jie LIU; Jiaping ZHANG

Chinese Journal of Plastic and Reconstructive Surgery (Jun 2021)

Electric Field: A Key Signal in Wound Healing

Naixin JIA,
Jinrui YANG,
Jie LIU,
Jiaping ZHANG

Affiliations

Naixin JIA: Department of Plastic and Aesthetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China
Jinrui YANG: Department of Plastic and Aesthetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China
Jie LIU: Department of Plastic and Aesthetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China
Jiaping ZHANG: Department of Plastic and Aesthetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China; Corresponding Author: Jiaping Zhang, MD Address: Department of Plastic and Aesthetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China, Tel.: 023-68754192

Journal volume & issue: Vol. 3, no. 2
pp. 95 – 102

Abstract

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SUMMARY: Wound healing is a complex biological process that involves proliferation, migration, and differentiation. Endogenous electric field (EF)-directed migration of keratinocytes (galvanotaxis) is an essential step in wound re-epithelialization. Endogenous EFs are generated instantaneously after an injury because of the collapse of transepithelial potentials. The application of exogenous EF has become increasingly widespread in promoting wound healing, leading to a paradigm shift in patient outcomes. Here, we summarize the role and value of EF in wound healing through a review of the current research.

Published in Chinese Journal of Plastic and Reconstructive Surgery

ISSN: 2096-6911 (Print); 2772-686X (Online)
Publisher: KeAi Communications Co. Ltd.
Country of publisher: China
LCC subjects: Medicine: Surgery
Website: https://www.keaipublishing.com/en/journals/chinese-journal-of-plastic-and-reconstructive-surgery/

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Abstract

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