Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale (Nov 2021)

THE COMPARATIVE ANALYSIS OF THE DRUG RESISTANCE OF MBTIN CHILDREN, ADOLESCENTS AND THE SOURCES OF INFECTION IN THE MULTIDRUG-RESISTANT TUBERCULOSIS FOCIES

  • Olha SAKHELASHVILI-BIL,
  • Manana SAKHELASHVILI

DOI
https://doi.org/10.52692/1857-0011.2021.3-71.18
Journal volume & issue
Vol. 71, no. 3
pp. 234 – 238

Abstract

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145 patients (67 children and 78 adolescents) from the multidrug-resistant tuberculosis infection focies took partin the complex microbiological study. The children and adolescents had undergone treatment for the pulmonary multidrug-resistant tuberculosis. The study showed that MDR TB was by 1.7 times more often revealed in the adolescents ascompared to the children, while the risk of MDR TB was by 3.7 times higher for the children than for the adolescents.The drug resistance profile of the children and the sources of infection almost completely coincided. The resistance toHRSE (66.1%) and HRESZ (13.6%) developed in the adolescents more often than in the children and adults. The studyproves the importance of defining the drug resistance profile in the exposed children and adolescents from the multidrug-resistant tuberculosis focies.

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