交叉性小脑神经机能联系不能1例报道并文献复习 Crossed Cerebellar Diaschisis: A Case Report and Literature Review

Abstract

交叉性小脑神经机能联系不能（crossed cerebellar diaschisis，CCD）是指当一侧大脑半球发生病变时，病灶对侧小脑半球出现血流量减少、葡萄糖氧化代谢水平下降的功能障碍，严重时甚至可能出现交叉性小脑萎缩的现象。CCD在临床工作中易被忽略或误诊。本文报告1例因左侧幕上脑梗死出现CCD导致左侧肢体共济失调以及认知功能障碍加重的病例，通过文献综述，阐明CCD的发生机制、临床特点及影响因素，为临床提供借鉴。 Abstract: The crossed cerebellar diaschisis (CCD) is a condition characterised by reduced blood flow and decreased oxidative metabolism of glucose in the contralateral cerebellar hemisphere following a lesion in one cerebral hemisphere, potentially resulting in crossed cerebellar atrophy in severe cases. It is easy to be overlooked or misdiagnosed in clinical practice. This paper presents a case of ataxia on the left side and worsening cognitive dysfunction resulting from left supratentorial cerebral infarction-induced CCD. The pathogenesis, clinical characteristics, and influencing factors of CCD were elucidated through the literature review to provide references for clinical practice.

Keywords

• 交叉性小脑神经机能联系不能
• 脑梗死
• 共济失调
• 认知功能障碍
• crossed cerebellar diaschisis
• cerebral infarction
• ataxia
• cognitive dysfunction