Engineering bioactive nanoparticles to rejuvenate vascular progenitor cells

Loan Bui; Shanique Edwards; Eva Hall; Laura Alderfer; Kellen Round; Madeline Owen; Pietro Sainaghi; Siyuan Zhang; Prakash D. Nallathamby; Laura S. Haneline; Donny Hanjaya-Putra

doi:10.1038/s42003-022-03578-4

Communications Biology (Jun 2022)

Engineering bioactive nanoparticles to rejuvenate vascular progenitor cells

Loan Bui,
Shanique Edwards,
Eva Hall,
Laura Alderfer,
Kellen Round,
Madeline Owen,
Pietro Sainaghi,
Siyuan Zhang,
Prakash D. Nallathamby,
Laura S. Haneline,
Donny Hanjaya-Putra

Affiliations

Loan Bui: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Shanique Edwards: Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health
Eva Hall: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Laura Alderfer: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Kellen Round: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Madeline Owen: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Pietro Sainaghi: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Siyuan Zhang: Department of Biological Science, University of Notre Dame
Prakash D. Nallathamby: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame
Laura S. Haneline: Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health
Donny Hanjaya-Putra: Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program, University of Notre Dame

DOI: https://doi.org/10.1038/s42003-022-03578-4
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

Read online

Drug-loaded liposomal nanoparticles conjugated to endothelial colony-forming cells can improve the vasculogenic potential of vascular progenitor cells exposed to gestational diabetes mellitus.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal