Plant hairy roots for the production of extracellular vesicles with antitumor bioactivity

Eleonora Boccia; Mariaevelina Alfieri; Raffaella Belvedere; Valentina Santoro; Marianna Colella; Pasquale Del Gaudio; Maria Moros; Fabrizio Dal Piaz; Antonello Petrella; Antonietta Leone; Alfredo Ambrosone

doi:10.1038/s42003-022-03781-3

Communications Biology (Aug 2022)

Plant hairy roots for the production of extracellular vesicles with antitumor bioactivity

Eleonora Boccia,
Mariaevelina Alfieri,
Raffaella Belvedere,
Valentina Santoro,
Marianna Colella,
Pasquale Del Gaudio,
Maria Moros,
Fabrizio Dal Piaz,
Antonello Petrella,
Antonietta Leone,
Alfredo Ambrosone

Affiliations

Eleonora Boccia: Department of Pharmacy, University of Salerno
Mariaevelina Alfieri: Department of Pharmacy, University of Salerno
Raffaella Belvedere: Department of Pharmacy, University of Salerno
Valentina Santoro: Department of Pharmacy, University of Salerno
Marianna Colella: Department of Pharmacy, University of Salerno
Pasquale Del Gaudio: Department of Pharmacy, University of Salerno
Maria Moros: Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza
Fabrizio Dal Piaz: Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno
Antonello Petrella: Department of Pharmacy, University of Salerno
Antonietta Leone: Department of Pharmacy, University of Salerno
Alfredo Ambrosone: Department of Pharmacy, University of Salerno

DOI: https://doi.org/10.1038/s42003-022-03781-3
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 10

Abstract

Read online

Extracellular vesicles isolated from Salvia dominica hairy roots have a small round-shaped morphology and carry typical EV-associated proteins, and demonstrate pro-apoptotic activity in pancreatic and breast cancer cells

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal