Alendronate-associated Polyarticular Synovitis: A Case Report

Abstract

Osteoporosis is a commonly observed systemic metabolic disease characterized by a decrease in bone mineral density and an increased risk of fractures worldwide. Bisphosphonates are commonly preferred for its prevention and treatment. Among the side effects of bisphosphonates used orally and parenterally are gastrointestinal symptoms, musculoskeletal pains, flu-like syndrome, and an increase in acute-phase reactants. In this case report, a rare side effect observed during alendronate treatment, polyarticular synovitis, will be presented.

Keywords

• osteoporosis
• synovitis
• alendronate
• bisphosphonate