Clinical and statistical indicators of the incidence of children born after in vitro fertilization

Abstract

Background. The state of health of children in modern society is changing under the influence of various factors and processes. To a large extent, this applies to children born through in vitro fertilization. This method of reproductive technology is considered the most effective and is evaluated by the effectiveness of childbirth. However, the most important aspect – the state of health of newborns after in vitro fertilization, remains unexplored.Objective. Purpose of the study was to identify the most significant pathological conditions in children with multiple and singleton pregnancies after in vitro fertilization.Materials and methods. The results of a clinical and laboratory study of children born in the Astrakhan region through in vitro fertilization for the period from 2016 to 2021, as well as follow-up data of children conceived through in vitro fertilization for 3 years, were studied. Methods of clinical (including somatometry), laboratory and statistical analysis were used.Results.116 children born through in vitro fertilization were examined, their somatometric parameters, Apgar score, morbidity and laboratory parameters were studied. It has been found that multiple pregnancies In vitro fertilization is a high risk factor for miscarriage and the occurrence of neonatal diseases such as preretinopathy and perinatal lesions of the nervous system. In addition, edematous syndrome, pyelonephritis, gestational diabetes and obesity in the anamnesis of mothers who decide to use the in vitro fertilization method for conception, with a high degree of probability predetermines miscarriage or the detection of perinatal lesions of the nervous system, anemia, preretinopathy in newborns.

Keywords

• in vitro fertilization
• newborns
• morbidity
• multiple pregnancies