Mìžnarodnij Endokrinologìčnij Žurnal (Oct 2016)

Morphometric and Biochemical Clusters of Metabolic Syndrome in Type 2 Diabetic Patients at Different Stages of Diabetic Retinopathy

  • V.N. Serdyuk,
  • V.A. Іshchenko

DOI
https://doi.org/10.22141/2224-0721.7.79.2016.86421
Journal volume & issue
Vol. 12, no. 7.79
pp. 69 – 74

Abstract

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Background. We studied the morphometric and biochemical clusters of metabolic syndrome in patients with type 2 diabetes mellitus (DM) at different stages of diabetic retinopathy (DR). Materials and methods. The study included 83 patients (166 eyes) divided into two groups. Results. The morphometric and biochemical clusters study of 59 patients with type 2 DM (mean age 58.2 ± 0.99 years old, the average duration of diabetes 9.19 ± 0.16 years) using dispersion analysis and binomial law demonstrated that DR developed in 83.4 % obsessive patients (with enhanced waist measurement), in 71.4 % hypertensive patients, in 61.9 % patients with hypercholesterinemia, 47.6 % patients with dyslipidemia and 52.3 % patients with hypertriglyceridemia. Further progression of DR is closely associated with hypertension, dyslipidemia against android obesity, hypercholesterolemia and hypertriglyceridemia. Conclusions. The patients with type 2 DM with the proliferative stage of DR are at increased risk of occurrence of cardiovascular events, including the ocular fundus. This should be considered in surgical, physiotherapy and medication treatment.

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