Communications Biology (Nov 2022)

Model simulations unveil the structure-function-dynamics relationship of the cerebellar cortical microcircuit

  • Robin De Schepper,
  • Alice Geminiani,
  • Stefano Masoli,
  • Martina Francesca Rizza,
  • Alberto Antonietti,
  • Claudia Casellato,
  • Egidio D’Angelo

DOI
https://doi.org/10.1038/s42003-022-04213-y
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 19

Abstract

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A computational modelling framework is developed, and used to reconstruct and simulate the entire cerebellar cortex, showing how mossy fibers entrain the neuronal microcircuit. This sheds light on local computation and neural correlates of behaviors