Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases

Yan He; Yi Wang; Kun Yang; Jia Jiao; Hong Zhan; Youjun Yang; De Lv; Weihong Li; Weijun Ding

doi:10.3390/molecules27248732

Molecules (Dec 2022)

Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases

Yan He,
Yi Wang,
Kun Yang,
Jia Jiao,
Hong Zhan,
Youjun Yang,
De Lv,
Weihong Li,
Weijun Ding

Affiliations

Yan He: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Yi Wang: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Kun Yang: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Jia Jiao: Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Hong Zhan: Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Youjun Yang: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
De Lv: Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Weihong Li: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China
Weijun Ding: Department of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Chengdu 611137, China

DOI: https://doi.org/10.3390/molecules27248732
Journal volume & issue: Vol. 27, no. 24
p. 8732

Abstract

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Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including olive, and is highly safe for human beings. In recent years, it has been reported that MA has anti-inflammatory, antioxidant, anti-tumor, hypoglycemic, neuroprotective and other biological activities. More and more experimental data has shown that MA has a good therapeutic effect on multiple organ diseases, indicating that it has great clinical application potential. In this paper, the extraction, purification, identification and analysis, biological activity, pharmacokinetics in vivo and molecular mechanism of MA in treating various organ diseases are reviewed. It is hoped to provide a new idea for MA to treat various organ diseases.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

About the journal

Abstract

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