Impact of frailty status on clinical outcomes in patients receiving peritoneal dialysis

Christy Abraham; Joanne Collier; Henry H.L. Wu; Joanne Martin; Helen Hurst; Dimitrios Poulikakos; David Lewis; Rajkumar Chinnadurai

Translational Medicine of Aging (Jan 2023)

Impact of frailty status on clinical outcomes in patients receiving peritoneal dialysis

Christy Abraham,
Joanne Collier,
Henry H.L. Wu,
Joanne Martin,
Helen Hurst,
Dimitrios Poulikakos,
David Lewis,
Rajkumar Chinnadurai

Affiliations

Christy Abraham: Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK
Joanne Collier: Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK
Henry H.L. Wu: Renal Research, Kolling Institute of Medical Research, Royal North Shore Hospital & the University of Sydney, Sydney, Australia
Joanne Martin: Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK
Helen Hurst: Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK; School of Health and Society, University of Salford, Salford, UK
Dimitrios Poulikakos: Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK; Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK
David Lewis: Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK; Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK
Rajkumar Chinnadurai: Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK; Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Salford, UK; Corresponding author. Donald O'Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Stott Lane, 6 8HD Salford, UK.

Journal volume & issue: Vol. 7
pp. 128 – 132

Abstract

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A cross-sectional analytical study was conducted for 88 patients receiving peritoneal dialysis (PD) in our centre over 13-months, to evaluate the ssociations between frailty and clinical outcomes within this context. Data on frailty status was prospectively determined based on the Clinical Frailty Scale. Our results found that a more severe frailty status, alongside being older and having more co-morbidities, were significant predictors of mortality in patients receiving PD. A multi-dimensional, yet individualized management approach is warranted for older PD patients living with frailty to optimize care.

Published in Translational Medicine of Aging

ISSN: 2468-5011 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Medicine
Website: https://www.keaipublishing.com/en/journals/translational-medicine-of-aging/

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