Nature Communications (Sep 2016)

Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans

  • Yang Wang,
  • Yi Zhang,
  • Lianwan Chen,
  • Qian Liang,
  • Xiao-Ming Yin,
  • Long Miao,
  • Byung-Ho Kang,
  • Ding Xue

DOI
https://doi.org/10.1038/ncomms12569
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 15

Abstract

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Autophagy mediates the degradation of paternal mitochondria after fertilization in C. elegansto ensure that mitochondria are inherited maternally. Here the authors show that mitochondrial dynamics is critical for the selectivity and kinetics of paternal mitochondrial elimination.