Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
Buket Erturk Sengel,
Elif Tukenmez Tigen,
Rabia Can Sarinoglu,
Ipek Midi,
Nilgun Cerikcioglu,
Zekaver Odabasi
Affiliations
Buket Erturk Sengel
Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, Turkey; Corresponding author at: Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Fevzi Çakmak Mah. Muhsin Yazıcıoğlu Cad. No:10, Pendik, İstanbul, Turkey.
Elif Tukenmez Tigen
Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, Turkey
Rabia Can Sarinoglu
Marmara University, Faculty of Medicine, Medical Microbiology, Istanbul, Turkey
Ipek Midi
Marmara University, Faculty of Medicine, Neurology, Istanbul, Turkey
Nilgun Cerikcioglu
Marmara University, Faculty of Medicine, Medical Microbiology, Istanbul, Turkey
Zekaver Odabasi
Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, Turkey
Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.
