IDCases (Jan 2021)

Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient

  • Buket Erturk Sengel,
  • Elif Tukenmez Tigen,
  • Rabia Can Sarinoglu,
  • Ipek Midi,
  • Nilgun Cerikcioglu,
  • Zekaver Odabasi

Journal volume & issue
Vol. 24
p. e01154

Abstract

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Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.

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