Journal of Patient-Reported Outcomes (Aug 2025)

The impact of vitreous floaters on quality of life: a qualitative study

  • Jarinne E. Woudstra-de Jong,
  • Sonia S. Manning-Charalampidou,
  • Johannes Hans R. Vingerling,
  • S. J. Feike Gerbrandy,
  • Konrad Pesudovs,
  • Jan J. Busschbach

DOI
https://doi.org/10.1186/s41687-025-00934-w
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Abstract Background In this study we explore the quality-of-life impact of vitreous floaters, and identify all possible issues that may be relevant to a person experiencing floaters, with the aim to define the content of a floaters-specific patient-reported outcome measure, which can help determine the disease burden and benefit of treatment for a patient with floaters. Methodology Semi-structured telephone interviews were conducted with patients with floaters. The topic guide was based on an extensive literature review and expert opinion. Interview transcripts were coded into all possible quality-of-life issues that may be relevant to a person experiencing floaters. We grouped these into quality-of-life domains and subdomains, using an earlier framework of quality of life in other ophthalmic diseases. Results We categorized the patients’ reports (N = 44) into 11 quality-of-life domains: activity limitations, visual symptoms, ocular symptoms, general symptoms, health concerns, emotional well-being, social well-being, mobility issues, economic impact, inconveniences, and the need to use coping strategies. Conclusions Vitreous floaters result in specific quality-of-life issues that have not been adequately measured with previous patient-reported outcome measures. When compared to other eye conditions, three previously unidentified issues stand out among patients with floaters: the effects of different lighting conditions, intermittent vision impairment caused by eye movements, and the importance of seeking understanding and support from healthcare providers. Eye care clinicians should recognize these issues when evaluating patients with floaters. The present patient-driven determination of relevant quality-of-life issues can guide initiatives in floaters-specific patient-reported outcome measures.

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