Omicron variant of SARS-CoV-2 imposes a new challenge for the global public health

Abstract

Since its first discovery, the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evoked another wave of infection and caused global concern and panic. Moreover, although the data are still limited, Omicron showed highly concerning characteristics, including higher transmissibility, extensive immune escape and potentially altered host range. We interpreted these characteristics based on currently available data and outlined some urgent questions, calling for a more comprehensive investigation.

Keywords

• SARS-CoV-2
• Omicron strain
• Immune escape
• Interspecies transmission