Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture

Abstract

The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a construct consisting of a polylactide scaffold and a human dermal fibroblasts culture. After implantation of TEC in the modeled defect area we analyzed the experimental group regeneration results in comparison to the control group.

Keywords

• гиалиновый хрящ
• дефект
• ткане-инженерная конструкция
• восстановление
• дермальные фибробласты