Nature Communications (Oct 2020)

Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock

  • Sarina Harshuk-Shabso,
  • Hila Dressler,
  • Christof Niehrs,
  • Emil Aamar,
  • David Enshell-Seijffers

DOI
https://doi.org/10.1038/s41467-020-18643-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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The underlying mechanisms regulating the mouse hair cycle remain poorly understood. Here, the authors find that Fgf and Wnt signaling pathways interact in the mesenchymal niche of the hair follicle to regulate the molecular clock that dictates the duration of hair growth.