Nature Communications (Jul 2018)

miR-103 promotes endothelial maladaptation by targeting lncWDR59

  • Lucia Natarelli,
  • Claudia Geißler,
  • Gergely Csaba,
  • Yuanyuan Wei,
  • Mengyu Zhu,
  • Andrea di Francesco,
  • Petra Hartmann,
  • Ralf Zimmer,
  • Andreas Schober

DOI
https://doi.org/10.1038/s41467-018-05065-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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MicroRNAs play important roles in endothelial cells injury, proliferation and maladaptation by negatively regulating posttranscriptional gene expression. Here the authors uncover the role of the long non coding RNA lncWDR59, target of miR-103, in endothelial maladaptation.