Bone Reports (Jun 2021)

Spontaneous bone infarction of the distal femur in a patient with Cushing's disease: a case report

  • Pepijn van Houten,
  • Jacky de Rooy,
  • Ingrid van der Geest,
  • Romana Netea-Maier,
  • Annenienke van de Ven

Journal volume & issue
Vol. 14
p. 100756

Abstract

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Avascular necrosis of the femoral head is a well-known complication of treatment with high dosage glucocorticoids and has been described in a few patients with Cushing's syndrome. In this case report, we describe the, to our knowledge, first case of a patient with endogenous Cushing's syndrome with a bone infarction located in the distal femur. In patients with Cushing's syndrome and bone pain, the diagnosis of bone infarction should be considered as it can occur as a rare complication of hypercortisolism.

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