RGUHS Journal of Pharmaceutical Sciences (Jan 2024)
Oral Anti-Coagulant (Acitrom) Induced Coagulopathy - A Case Report
Abstract
The major complication of oral anticoagulants is bleeding. Acitrom Acenocoumarol an oral anticoagulant is similar to Warfarin but has a longer half-life with fewer interactions. To reduce the risk of these complications the Prothrombin time PT ndash usually expressed as the International Normalized Ratio INR is used to monitor the degree of Acenocoumarol or coumarin-associated anticoagulation. In our study a 50 year old male patient presented with a complaint of ecchymosis over abdomen and thigh and hematuria since five days. The patient was on T. Acitrom 4 mg with a history of open-heart surgery 20 years back. On analyzing the subjective and objective evidences the condition was diagnosed as lsquoAcitrom Induced Coagulopathyrsquo which was confirmed using WHO-UMC Uppsala Monitoring Centre Causality Assessment Scale Naranjo Scale Score and Karch and Lasagna scale.