ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice

Nicole L. Batenburg; John R. Walker; Sylvie M. Noordermeer; Nathalie Moatti; Daniel Durocher; Xu-Dong Zhu

doi:10.1038/s41467-017-02114-x

Nature Communications (Dec 2017)

ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice

Nicole L. Batenburg,
John R. Walker,
Sylvie M. Noordermeer,
Nathalie Moatti,
Daniel Durocher,
Xu-Dong Zhu

Affiliations

Nicole L. Batenburg: Department of Biology, McMaster University, Hamilton
John R. Walker: Department of Biology, McMaster University, Hamilton
Sylvie M. Noordermeer: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto
Nathalie Moatti: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto
Daniel Durocher: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto
Xu-Dong Zhu: Department of Biology, McMaster University, Hamilton

DOI: https://doi.org/10.1038/s41467-017-02114-x
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 17

Abstract

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Cockayne syndrome group B protein (CSB) is a multifunctional chromatin remodeler involved in double-strand break repair. Here the authors investigate the molecular post-translational signals regulating CSB activity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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