The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19

• Francesco Scavello,
• Enrico Brunetta,
• Sarah N. Mapelli,
• Emanuele Nappi,
• Ian David García Martín,
• Marina Sironi,
• Roberto Leone,
• Simone Solano,
• Giovanni Angelotti,
• Domenico Supino,
• Silvia Carnevale,
• Hang Zhong,
• Elena Magrini,
• Matteo Stravalaci,
• Alessandro Protti,
• Alessandro Santini,
• Elena Costantini,
• Victor Savevski,
• Antonio Voza,
• Barbara Bottazzi,
• Michele Bartoletti,
• Maurizio Cecconi,
• Alberto Mantovani,
• Paola Morelli,
• Federica Tordato,
• Cecilia Garlanda

Affiliations

Francesco Scavello

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Enrico Brunetta

Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy

Sarah N. Mapelli

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Emanuele Nappi

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy

Ian David García Martín

Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy

Marina Sironi

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Roberto Leone

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Simone Solano

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Giovanni Angelotti

Artificial Intelligence Center, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Domenico Supino

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Silvia Carnevale

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Hang Zhong

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy

Elena Magrini

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Matteo Stravalaci

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Alessandro Protti

Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Alessandro Santini

Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Elena Costantini

Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Victor Savevski

Artificial Intelligence Center, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Antonio Voza

Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Emergency Department, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Barbara Bottazzi

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Michele Bartoletti

Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy

Maurizio Cecconi

Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy

Alberto Mantovani

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; The William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK

Paola Morelli

Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy

Federica Tordato

Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy

Cecilia Garlanda

IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Corresponding author. IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.