Journal of Clinical and Scientific Research (Jan 2023)

Prevalence of metallo beta-lactamase and Amp C beta-lactamase producing pathogens causing surgical site infection in a tertiary care teaching centre in Southern India

  • R Bindu Madhavi,
  • A R Hanumanthappa

DOI
https://doi.org/10.4103/jcsr.jcsr_70_22
Journal volume & issue
Vol. 12, no. 5
pp. 27 – 32

Abstract

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Background: Surgical site infection (SSI) is the most common type of hospital-acquired infection-causing public health problems. The study was undertaken to know the aerobic bacteriology of SSI with special reference to the detection of metallo-beta-lactamase (MBL) and AmpC beta-lactamases among Gram-negative bacilli. Methods: The present cross-sectional study was conducted in 140 patients clinically suspected to have SSIs. Samples were collected from patients after considering inclusion and exclusion criteria. Results: Out of 85 Gram-negative bacilli, 9 isolates (10.6%) were Amp C producers. Out of a total of 85 Gram-negative bacilli, 3 isolates (3.5%) were MBL producers. Two isolates of Pseudomonas aeruginosa and 1 isolate of Acinetobacter spp. were positive for MBL production. In the present study, MBL production was seen in 3.5%, of Gram-negative bacilli. Conclusions: Early identification of such resistant strains is important to plan the appropriate antibiotic therapy. Strict infection control practices and judicious use of available antibiotics are essential to prevent the emergence of multidrug-resistant strains.

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